Vascular dysfunction promotes regional hypoxia after bevacizumab therapy in recurrent glioblastoma patients

BACKGROUND: Hypoxia is a driver of treatment resistance in glioblastoma. Antiangiogenic agents may transiently normalize blood vessels and decrease hypoxia before excessive pruning of vessels increases hypoxia. The time window of normalization is dose and time dependent. We sought to determine how V...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Gerstner, Elizabeth R, Emblem, Kyrre E, Yen, Yi-Fen, Dietrich, Jorg, Jordan, Justin T, Catana, Ciprian, Wenchin, Kevin Lou, Hooker, Jacob M, Duda, Dan G, Rosen, Bruce R, Kalpathy-Cramer, Jayashree, Jain, Rakesh K, Batchelor, Tracy T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764510/
https://ncbi.nlm.nih.gov/pubmed/33392506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa157
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados