Mechanisms of EMRE-Dependent MCU Opening in the Mitochondrial Calcium Uniporter Complex

The mitochondrial calcium uniporter is a multi-subunit Ca(2+)-activated Ca(2+) channel, made up of the pore-forming MCU protein, a metazoan-specific EMRE subunit, and MICU1/MICU2, which mediate Ca(2+) activation. It has been established that metazoan MCU requires EMRE binding to conduct Ca(2+), but...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Van Keuren, Anna M., Tsai, Chen-Wei, Balderas, Enrique, Rodriguez, Madison X., Chaudhuri, Dipayan, Tsai, Ming-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764451/
https://ncbi.nlm.nih.gov/pubmed/33296646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108486
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky