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The Failed Clinical Story of Myostatin Inhibitors against Duchenne Muscular Dystrophy: Exploring the Biology behind the Battle

Myostatin inhibition therapy has held much promise for the treatment of muscle wasting disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy (DMD). Following on from promising pre-clinical data in dystrophin-deficient mice and dogs, several clinical trials were ini...

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Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: Rybalka, Emma, Timpani, Cara A., Debruin, Danielle A., Bagaric, Ryan M., Campelj, Dean G., Hayes, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764137/
https://ncbi.nlm.nih.gov/pubmed/33322031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122657
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