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The Failed Clinical Story of Myostatin Inhibitors against Duchenne Muscular Dystrophy: Exploring the Biology behind the Battle

Myostatin inhibition therapy has held much promise for the treatment of muscle wasting disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy (DMD). Following on from promising pre-clinical data in dystrophin-deficient mice and dogs, several clinical trials were ini...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Rybalka, Emma, Timpani, Cara A., Debruin, Danielle A., Bagaric, Ryan M., Campelj, Dean G., Hayes, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764137/
https://ncbi.nlm.nih.gov/pubmed/33322031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122657
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