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Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature

BACKGROUND: The blood‐brain barrier (BBB) is critical for cerebrovascular health. Although aging impairs the integrity of the BBB, the mechanisms behind this phenomenon are not clear. As mitochondrial components activate inflammation as mitochondria become dysfunctional, we examined how aging impact...

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Podrobná bibliografie
Vydáno v:J Am Heart Assoc
Hlavní autoři: Tyrrell, Daniel J., Blin, Muriel G., Song, Jianrui, Wood, Sherri C., Goldstein, Daniel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763766/
https://ncbi.nlm.nih.gov/pubmed/33225820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.017820
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