Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription

Thoracic great vessels such as the aorta and subclavian arteries are formed through dynamic remodeling of embryonic pharyngeal arch arteries (PAAs). Previous work has shown that loss of a basic helix-loop-helix transcription factor Hey1 in mice causes abnormal fourth PAA development and lethal great...

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Udgivet i:J Biol Chem
Main Authors: Watanabe, Yusuke, Seya, Daiki, Ihara, Dai, Ishii, Shuhei, Uemoto, Taiki, Kubo, Atsushi, Arai, Yuji, Isomoto, Yoshie, Nakano, Atsushi, Abe, Takaya, Shigeta, Mayo, Kawamura, Teruhisa, Saito, Yoshihiko, Ogura, Toshihiko, Nakagawa, Osamu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762959/
https://ncbi.nlm.nih.gov/pubmed/33454003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015003
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