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The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance

The development of a chronic, low-grade inflammation originating from adipose tissue in obese subjects is widely recognized to induce insulin resistance, leading to the development of type 2 diabetes. The adipose tissue microenvironment drives specific metabolic reprogramming of adipose tissue macro...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: van Dierendonck, Xanthe A. M. H., Sancerni, Tiphaine, Alves-Guerra, Marie-Clotilde, Stienstra, Rinke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762953/
https://ncbi.nlm.nih.gov/pubmed/33453996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014868
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