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Physiologically‐Based Pharmacokinetic Modelling of Creatinine‐Drug Interactions in the Chronic Kidney Disease Population

Elevated serum creatinine (S(Cr)) caused by the inhibition of renal transporter(s) may be misinterpreted as kidney injury. The interpretation is more complicated in patients with chronic kidney disease (CKD) due to altered disposition of creatinine and renal transporter inhibitors. A clinical study...

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Bibliografische gegevens
Gepubliceerd in:CPT Pharmacometrics Syst Pharmacol
Hoofdauteurs: Takita, Hiroyuki, Scotcher, Daniel, Chinnadurai, Rajkumar, Kalra, Philip A., Galetin, Aleksandra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762809/
https://ncbi.nlm.nih.gov/pubmed/33049120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12566
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