Physiologically‐Based Pharmacokinetic Modelling of Creatinine‐Drug Interactions in the Chronic Kidney Disease Population

Elevated serum creatinine (S(Cr)) caused by the inhibition of renal transporter(s) may be misinterpreted as kidney injury. The interpretation is more complicated in patients with chronic kidney disease (CKD) due to altered disposition of creatinine and renal transporter inhibitors. A clinical study...

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Detaylı Bibliyografya
Yayımlandı:CPT Pharmacometrics Syst Pharmacol
Asıl Yazarlar: Takita, Hiroyuki, Scotcher, Daniel, Chinnadurai, Rajkumar, Kalra, Philip A., Galetin, Aleksandra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762809/
https://ncbi.nlm.nih.gov/pubmed/33049120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12566
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