Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons

Hydroxychloroquine is being investigated for a potential prophylactic effect in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but its mechanism of action is poorly understood. Circulating leukocytes from the blood of coronavirus disease 2019 (COVID-19) patients show increas...

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Publicado no:Cell Rep Med
Main Authors: Rother, Nils, Yanginlar, Cansu, Lindeboom, Rik G.H., Bekkering, Siroon, van Leent, Mandy M.T., Buijsers, Baranca, Jonkman, Inge, de Graaf, Mark, Baltissen, Marijke, Lamers, Lieke A., Riksen, Niels P., Fayad, Zahi A., Mulder, Willem J.M., Hilbrands, Luuk B., Joosten, Leo A.B., Netea, Mihai G., Vermeulen, Michiel, van der Vlag, Johan, Duivenvoorden, Raphaël
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762774/
https://ncbi.nlm.nih.gov/pubmed/33377122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100146
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