Increased Plasma Heparanase Activity in COVID-19 Patients

Reports suggest a role of endothelial dysfunction and loss of endothelial barrier function in COVID-19. It is well established that the endothelial glycocalyx-degrading enzyme heparanase contributes to vascular leakage and inflammation. Low molecular weight heparins (LMWH) serve as an inhibitor of h...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Buijsers, Baranca, Yanginlar, Cansu, de Nooijer, Aline, Grondman, Inge, Maciej-Hulme, Marissa L., Jonkman, Inge, Janssen, Nico A. F., Rother, Nils, de Graaf, Mark, Pickkers, Peter, Kox, Matthijs, Joosten, Leo A. B., Nijenhuis, Tom, Netea, Mihai G., Hilbrands, Luuk, van de Veerdonk, Frank L., Duivenvoorden, Raphaël, de Mast, Quirijn, van der Vlag, Johan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573491/
https://ncbi.nlm.nih.gov/pubmed/33123154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.575047
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