CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1

Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance significantly limits its therapeutic efficacy, and the mechanisms underlying resistance have not been fully clarified. Here we report that a circular RNA, circRNA-SORE (a c...

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Détails bibliographiques
Publié dans:Signal Transduct Target Ther
Auteurs principaux: Xu, Junjie, Ji, Lin, Liang, Yuelong, Wan, Zhe, Zheng, Wei, Song, Xiaomin, Gorshkov, Kirill, Sun, Qiming, Lin, Hui, Zheng, Xueyong, Chen, Jiang, Jin, Ren-an, Liang, Xiao, Cai, Xiujun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762756/
https://ncbi.nlm.nih.gov/pubmed/33361760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00375-5
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