N(6)-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling

BACKGROUND AND AIMS: Accumulating evidence suggests that the primary and acquired resistance of hepatocellular carcinoma (HCC) to sorafenib is mediated by multiple molecular, cellular, and microenvironmental mechanisms. Understanding these mechanisms will enhance the likelihood of effective sorafeni...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cancer
Auteurs principaux: Xu, Junjie, Wan, Zhe, Tang, Minyue, Lin, Zhongjie, Jiang, Shi, Ji, Lin, Gorshkov, Kirill, Mao, Qijiang, Xia, Shunjie, Cen, Dong, Zheng, Junhao, Liang, Xiao, Cai, Xiujun
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681956/
https://ncbi.nlm.nih.gov/pubmed/33222692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01281-8
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