Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy

The leading cause of death in pulmonary arterial hypertension (PAH) is right ventricular (RV) failure (RVF). Reactive oxygen species (ROS) have been suggested to play a role in the development of RV hypertrophy (RVH) and the transition to RVF. The hydrogen peroxide-generating protein p66shc has been...

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Udgivet i:Int J Mol Sci
Main Authors: Hirschhäuser, Christine, Sydykov, Akylbek, Wolf, Annemarie, Esfandiary, Azadeh, Bornbaum, Julia, Kutsche, Hanna Sarah, Boengler, Kerstin, Sommer, Natascha, Schreckenberg, Rolf, Schlüter, Klaus-Dieter, Weissmann, Norbert, Schermuly, Ralph, Schulz, Rainer
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762598/
https://ncbi.nlm.nih.gov/pubmed/33302436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249339
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