Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle

Skeletal muscle atrophy, which occurs in lipopolysaccharide (LPS)-induced sepsis, causes a severe muscle function reduction. The increased autophagy contributes to sepsis-induced skeletal muscle atrophy in a model of LPS injection, increasing LC3II/LC3I ratio, autophagy flux, and autophagosomes. Ang...

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Publicat a:Int J Mol Sci
Autors principals: Rivera, Juan Carlos, Abrigo, Johanna, Tacchi, Franco, Simon, Felipe, Brandan, Enrique, Santos, Robson A., Bader, Michael, Chiong, Mario, Cabello-Verrugio, Claudio
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762589/
https://ncbi.nlm.nih.gov/pubmed/33302427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249344
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