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Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles

Connective tissue growth factor (CTGF/CCN-2) is mainly involved in the induction of extracellular matrix (ECM) proteins. The levels of CTGF correlate with the degree and severity of fibrosis in many tissues, including dystrophic skeletal muscle. The CTGF overexpression in tibialis anterior skeletal...

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Bibliografiske detaljer
Main Authors: Cabello-Verrugio, Claudio, Morales, María Gabriela, Cabrera, Daniel, Vio, Carlos P, Brandan, Enrique
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822846/
https://ncbi.nlm.nih.gov/pubmed/21645240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01354.x
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