E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc

FBXW7 functions as an E3 ubiquitin ligase to mediate oncoprotein degradation via the ubiquitin-proteasome system in cancer cells, effectively inhibiting the growth and survival of tumor cells. However, little is known about the functions of FBXW7 in macrophages and the tumor immune microenvironment....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging (Albany NY)
Egile Nagusiak: Zhong, Lijia, Zhang, Yuanyuan, Li, Mengyao, Song, Yinjing, Liu, Danhui, Yang, Xin, Yang, Dehua, Qu, Hao, Lai, Lihua, Wang, Qingqing, Chen, Zhimin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals 2020
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762499/
https://ncbi.nlm.nih.gov/pubmed/33260160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202293
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