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Exploring the mechanism of resistance to sorafenib in two hepatocellular carcinoma cell lines

Sorafenib has long been the only approved systemic therapy for advanced hepatocellular carcinoma (HCC), but most patients show primary or acquired drug resistance. In the present study, RNA was extracted from sorafenib-resistant and -sensitive clones of the HCC cell lines HepG2 and Huh7. Protein-pro...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhang, Zhi, He, Cheng-Zu, Qin, Ya-Qin, Liao, Jian-Jun, Huang, Shang-Tao, Mo, Steven, Li, Hong-Mian, Lin, Jian-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762478/
https://ncbi.nlm.nih.gov/pubmed/33234725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104195
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