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Exploring the mechanism of resistance to sorafenib in two hepatocellular carcinoma cell lines

Sorafenib has long been the only approved systemic therapy for advanced hepatocellular carcinoma (HCC), but most patients show primary or acquired drug resistance. In the present study, RNA was extracted from sorafenib-resistant and -sensitive clones of the HCC cell lines HepG2 and Huh7. Protein-pro...

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Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: Zhang, Zhi, He, Cheng-Zu, Qin, Ya-Qin, Liao, Jian-Jun, Huang, Shang-Tao, Mo, Steven, Li, Hong-Mian, Lin, Jian-Yan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762478/
https://ncbi.nlm.nih.gov/pubmed/33234725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104195
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