Circulating Methylated DNA to Monitor the Dynamics of RAS Mutation Clearance in Plasma from Metastatic Colorectal Cancer Patients

SIMPLE SUMMARY: Ongoing clinical trials are recently investigating the efficacy of second-line EGFR inhibitors in initially RAS mutant metastatic colorectal cancer patients who convert to RAS wild-type in plasma, as assessed by circulating tumor DNA (ctDNA) analysis. To this purpose, discriminating...

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Опубликовано в: :Cancers (Basel)
Главные авторы: Nicolazzo, Chiara, Barault, Ludovic, Caponnetto, Salvatore, Macagno, Marco, De Renzi, Gianluigi, Gradilone, Angela, Belardinilli, Francesca, Cortesi, Enrico, Di Nicolantonio, Federica, Gazzaniga, Paola
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Brief Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761880/
https://ncbi.nlm.nih.gov/pubmed/33291569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123633
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