Effect of Heme Oxygenase-1 on Melanoma Development in Mice—Role of Tumor-Infiltrating Immune Cells

Objective: Heme oxygenase-1 (HO-1) is a cytoprotective, proangiogenic and anti-inflammatory enzyme that is often upregulated in tumors. Overexpression of HO-1 in melanoma cells leads to enhanced tumor growth, augmented angiogenesis and resistance to anticancer treatment. The effect of HO-1 in host c...

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Published in:Antioxidants (Basel)
Main Authors: Was, Halina, Cichon, Tomasz, Smolarczyk, Ryszard, Lackowska, Bozena, Mazur-Bialy, Agnieszka, Mazur, Magdalena, Szade, Agata, Dominik, Pawel, Mazan, Milena, Kotlinowski, Jerzy, Zebzda, Anna, Kusienicka, Anna, Kieda, Claudine, Dulak, Jozef, Jozkowicz, Alicja
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761646/
https://ncbi.nlm.nih.gov/pubmed/33287312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121223
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