Overexpression of Heme Oxygenase-1 in Murine Melanoma : Increased Proliferation and Viability of Tumor Cells, Decreased Survival of Mice

Heme oxygenase-1 (HO-1), a cytoprotective enzyme, can be induced in tumors in response to anti-cancer therapies. We investigated the role of HO-1 in B16(F10), S91, and Sk-mel188 melanoma cells. Overexpression of HO-1 after transduction with adenoviral vectors increased cell proliferation, resistance...

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Main Authors: Was, Halina, Cichon, Tomasz, Smolarczyk, Ryszard, Rudnicka, Dominika, Stopa, Magdalena, Chevalier, Catherine, Leger, Jean J., Lackowska, Bozena, Grochot, Anna, Bojkowska, Karolina, Ratajska, Anna, Kieda, Claudine, Szala, Stanislaw, Dulak, Jozef, Jozkowicz, Alicja
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2006
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762485/
https://ncbi.nlm.nih.gov/pubmed/17148680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051365
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