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Five Italian Families with Two Mutations in BRCA Genes

Double heterozygosity (DH) in BRCA1 and BRCA2 genes and double mutation (DM) in BRCA1 or BRCA2 are extremely rare events in the general population, and few cases have been reported worldwide so far. Here, we describe five probands, all women, with breast and/or ovarian cancer and their families. Par...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Vietri, Maria Teresa, Caliendo, Gemma, D’Elia, Giovanna, Resse, Marianna, Casamassimi, Amelia, Minucci, Pellegrino Biagio, Dello Ioio, Concetta, Cioffi, Michele, Molinari, Anna Maria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761639/
https://ncbi.nlm.nih.gov/pubmed/33287145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11121451
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