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Five Italian Families with Two Mutations in BRCA Genes

Double heterozygosity (DH) in BRCA1 and BRCA2 genes and double mutation (DM) in BRCA1 or BRCA2 are extremely rare events in the general population, and few cases have been reported worldwide so far. Here, we describe five probands, all women, with breast and/or ovarian cancer and their families. Par...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes (Basel)
Hauptverfasser: Vietri, Maria Teresa, Caliendo, Gemma, D’Elia, Giovanna, Resse, Marianna, Casamassimi, Amelia, Minucci, Pellegrino Biagio, Dello Ioio, Concetta, Cioffi, Michele, Molinari, Anna Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761639/
https://ncbi.nlm.nih.gov/pubmed/33287145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11121451
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