Proteomic Characterization of Synaptosomes from Human Substantia Nigra Indicates Altered Mitochondrial Translation in Parkinson’s Disease

The pathological hallmark of Parkinson’s disease (PD) is the loss of neuromelanin-containing dopaminergic neurons within the substantia nigra pars compacta (SNpc). Additionally, numerous studies indicate an altered synaptic function during disease progression. To gain new insights into the molecular...

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Publicado en:Cells
Autores principales: Plum, Sarah, Eggers, Britta, Helling, Stefan, Stepath, Markus, Theiss, Carsten, Leite, Renata E. P., Molina, Mariana, Grinberg, Lea T., Riederer, Peter, Gerlach, Manfred, May, Caroline, Marcus, Katrin
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761546/
https://ncbi.nlm.nih.gov/pubmed/33276480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122580
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