Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination

Demyelinated lesions in human pons observed after osmotic shifts in serum have been referred to as central pontine myelinolysis (CPM). Astrocytic damage, which is prominent in neuroinflammatory diseases like neuromyelitis optica (NMO) and multiple sclerosis (MS), is considered the primary event duri...

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Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Lohrberg, Melanie, Winkler, Anne, Franz, Jonas, van der Meer, Franziska, Ruhwedel, Torben, Sirmpilatze, Nikoloz, Dadarwal, Rakshit, Handwerker, Ronja, Esser, Daniel, Wiegand, Kerstin, Hagel, Christian, Gocht, Andreas, König, Fatima Barbara, Boretius, Susann, Möbius, Wiebke, Stadelmann, Christine, Barrantes-Freer, Alonso
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761156/
https://ncbi.nlm.nih.gov/pubmed/33357244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01105-2
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