Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination

Demyelinated lesions in human pons observed after osmotic shifts in serum have been referred to as central pontine myelinolysis (CPM). Astrocytic damage, which is prominent in neuroinflammatory diseases like neuromyelitis optica (NMO) and multiple sclerosis (MS), is considered the primary event duri...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Lohrberg, Melanie, Winkler, Anne, Franz, Jonas, van der Meer, Franziska, Ruhwedel, Torben, Sirmpilatze, Nikoloz, Dadarwal, Rakshit, Handwerker, Ronja, Esser, Daniel, Wiegand, Kerstin, Hagel, Christian, Gocht, Andreas, König, Fatima Barbara, Boretius, Susann, Möbius, Wiebke, Stadelmann, Christine, Barrantes-Freer, Alonso
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761156/
https://ncbi.nlm.nih.gov/pubmed/33357244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01105-2
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