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Analysis of Biological Screening Compounds with Single- or Multi-Target Activity via Diagnostic Machine Learning

Predicting compounds with single- and multi-target activity and exploring origins of compound specificity and promiscuity is of high interest for chemical biology and drug discovery. We present a large-scale analysis of compound promiscuity including two major components. First, high-confidence data...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Feldmann, Christian, Yonchev, Dimitar, Bajorath, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761051/
https://ncbi.nlm.nih.gov/pubmed/33260876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121605
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