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Tree-Based QSAR Model for Drug Repurposing in the Discovery of New Antibacterial Compounds against Escherichia coli

Drug repurposing appears as an increasing popular tool in the search of new treatment options against bacteria. In this paper, a tree-based classification method using Linear Discriminant Analysis (LDA) and discrete indexes was used to create a QSAR (Quantitative Structure-Activity Relationship) mod...

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Publicat a:Pharmaceuticals (Basel)
Autors principals: Suay-Garcia, Beatriz, Falcó, Antonio, Bueso-Bordils, J. Ignacio, Anton-Fos, Gerardo M., Pérez-Gracia, M. Teresa, Alemán-López, Pedro A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760995/
https://ncbi.nlm.nih.gov/pubmed/33260726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13120431
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