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Molecular Topology for the Discovery of New Broad-Spectrum Antibacterial Drugs

In this study, molecular topology was used to develop several discriminant equations capable of classifying compounds according to their antibacterial activity. Topological indices were used as structural descriptors and their relation to antibacterial activity was determined by applying linear disc...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Bueso-Bordils, Jose I., Alemán-López, Pedro A., Suay-García, Beatriz, Martín-Algarra, Rafael, Duart, Maria J., Falcó, Antonio, Antón-Fos, Gerardo M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564208/
https://ncbi.nlm.nih.gov/pubmed/32961733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091343
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