Chronic High Glucose Concentration Induces Inflammatory and Remodeling Changes in Valvular Endothelial Cells and Valvular Interstitial Cells in a Gelatin Methacrylate 3D Model of the Human Aortic Valve

Calcific aortic valve disease (CAVD), a degenerative disease characterized by inflammation, fibrosis and calcification, is accelerated in diabetes. Hyperglycemia contributes to this process by mechanisms that still need to be uncovered. We have recently developed a 3D model of the human aortic valve...

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Vydáno v:Polymers (Basel)
Hlavní autoři: Ciortan, Letitia, Macarie, Razvan Daniel, Cecoltan, Sergiu, Vadana, Mihaela, Tucureanu, Monica Madalina, Mihaila, Andreea Cristina, Droc, Ionel, Butoi, Elena, Manduteanu, Ileana
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760928/
https://ncbi.nlm.nih.gov/pubmed/33255639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym12122786
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