Synthesis, Biological, and Computational Evaluation of Antagonistic, Chiral Hydrobenzoin Esters of Arecaidine Targeting mAChR M1

Muscarinic acetylcholine receptors (mAChRs) are a pivotal constituent of the central and peripheral nervous system. Yet, therapeutic and diagnostic applications thereof are hampered by the lack of subtype selective ligands. Within this work, we synthesized and chemically characterized three differen...

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Detaylı Bibliyografya
Yayımlandı:Pharmaceuticals (Basel)
Asıl Yazarlar: Ozenil, Marius, Aronow, Jonas, Piljak, Daniela, Vraka, Chrysoula, Holzer, Wolfgang, Spreitzer, Helmut, Wadsak, Wolfgang, Hacker, Marcus, Pichler, Verena
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760838/
https://ncbi.nlm.nih.gov/pubmed/33266067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13120437
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