Agonist mediated internalization of M(2 )mAChR is β-arrestin-dependent

BACKGROUND: Muscarinic acetylcholine receptors (mAChRs) undergo agonist-promoted internalization, but evidence suggesting that the mechanism of internalization is β-arrestin dependent has been contradictory and unclear. Previous studies using heterologous over-expression of wild type or dominant-neg...

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Autori principali: Jones, Kymry T, Echeverry, Maria, Mosser, Valerie A, Gates, Alicia, Jackson, Darrell A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769497/
https://ncbi.nlm.nih.gov/pubmed/17224084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-1-7
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