ASC-Mediated Inflammation and Pyroptosis Attenuates Brucella abortus Pathogenesis Following the Recognition of gDNA

Brucella abortus is a zoonotic pathogen that causes brucellosis. Because of Brucella’s unique LPS layer and intracellular localization predominately within macrophages, it can often evade immune detection. However, pattern recognition receptors are capable of sensing Brucella pathogen-associated mol...

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Udgivet i:Pathogens
Main Authors: Tupik, Juselyn D., Coutermarsh-Ott, Sheryl L., Benton, Angela H., King, Kellie A., Kiryluk, Hanna D., Caswell, Clayton C., Allen, Irving C.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760712/
https://ncbi.nlm.nih.gov/pubmed/33266295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9121008
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