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ASC-Mediated Inflammation and Pyroptosis Attenuates Brucella abortus Pathogenesis Following the Recognition of gDNA

Brucella abortus is a zoonotic pathogen that causes brucellosis. Because of Brucella’s unique LPS layer and intracellular localization predominately within macrophages, it can often evade immune detection. However, pattern recognition receptors are capable of sensing Brucella pathogen-associated mol...

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Détails bibliographiques
Publié dans:Pathogens
Auteurs principaux: Tupik, Juselyn D., Coutermarsh-Ott, Sheryl L., Benton, Angela H., King, Kellie A., Kiryluk, Hanna D., Caswell, Clayton C., Allen, Irving C.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760712/
https://ncbi.nlm.nih.gov/pubmed/33266295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9121008
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