Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis

SIMPLE SUMMARY: Lung cancer is one of the most commonly diagnosed cancers worldwide and the most common cause of cancer-related deaths. During lung carcinogenesis, epigenetic alteration of tumor-related genes is a frequent event and especially silencing of tumor suppressor genes is often found. In o...

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Udgivet i:Cancers (Basel)
Main Authors: Küster, Miriam M., Schneider, Marc A., Richter, Antje M., Richtmann, Sarah, Winter, Hauke, Kriegsmann, Mark, Pullamsetti, Soni S., Stiewe, Thorsten, Savai, Rajkumar, Muley, Thomas, Dammann, Reinhard H.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760495/
https://ncbi.nlm.nih.gov/pubmed/33256112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123528
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