“Metaphilic” Cell-Penetrating Polypeptide-Vancomycin Conjugate Efficiently Eradicates Intracellular Bacteria via a Dual Mechanism

[Image: see text] Infections by intracellular pathogens are difficult to treat because of the poor accessibility of antibiotics to the pathogens encased by host cell membranes. As such, a strategy that can improve the membrane permeability of antibiotics would significantly increase their efficiency...

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Pubblicato in:ACS Cent Sci
Autori principali: Jiang, Yunjiang, Han, Ming, Bo, Yang, Feng, Yujun, Li, Wenming, Wu, Jason Ren, Song, Ziyuan, Zhao, Zihao, Tan, Zhengzhong, Chen, Yingying, Xue, Tianrui, Fu, Zihuan, Kuo, Shanny Hsuan, Lau, Gee W., Luijten, Erik, Cheng, Jianjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2020
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760462/
https://ncbi.nlm.nih.gov/pubmed/33376787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c00893
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