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RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGFβ1 in the Suppression of Cell Motility

SIMPLE SUMMARY: Transforming growth factor (TGF)β secreted by cancer cells and acting in an autostimulatory manner has been implicated in epithelial-mesenchymal transition and cellular invasion. However, the upstream inducers/downstream effectors, or the effects on cell migration, of endogenously pr...

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Publicado en:Cancers (Basel)
Autores principales: Ungefroren, Hendrik, Otterbein, Hannah, Wellner, Ulrich F., Keck, Tobias, Lehnert, Hendrik, Marquardt, Jens-Uwe
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760153/
https://ncbi.nlm.nih.gov/pubmed/33260366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123570
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