Solid Lipid Nanoparticles as Formulative Strategy to Increase Oral Permeation of a Molecule Active in Multidrug-Resistant Tuberculosis Management

The role of mycobacterial efflux pumps in drug-resistant tuberculosis has been widely reported. Recently, a new compound, named SS13, has been synthesized, and its activity as a potential efflux inhibitor has been demonstrated. In this work, the chemical–physical properties of the SS13 were investig...

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Vydáno v:Pharmaceutics
Hlavní autoři: Obinu, Antonella, Porcu, Elena Piera, Piras, Sandra, Ibba, Roberta, Carta, Antonio, Molicotti, Paola, Migheli, Rossana, Dalpiaz, Alessandro, Ferraro, Luca, Rassu, Giovanna, Gavini, Elisabetta, Giunchedi, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760137/
https://ncbi.nlm.nih.gov/pubmed/33255304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121132
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