The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model

SIMPLE SUMMARY: We have developed a new boron compound for application in boron neutron capture therapy (BNCT) named boronophenylalanine–amide alkyl dodecaborate (BADB). It is characterized by a larger amount of (10)B per molecule, linking boronphenylalanine (BPA) and dodecaborate, and we conducted...

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Pubblicato in:Biology (Basel)
Autori principali: Fukuo, Yusuke, Hattori, Yoshihide, Kawabata, Shinji, Kashiwagi, Hideki, Kanemitsu, Takuya, Takeuchi, Koji, Futamura, Gen, Hiramatsu, Ryo, Watanabe, Tsubasa, Hu, Naonori, Takata, Takushi, Tanaka, Hiroki, Suzuki, Minoru, Miyatake, Shin-Ichi, Kirihata, Mitsunori, Wanibuchi, Masahiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759915/
https://ncbi.nlm.nih.gov/pubmed/33271972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9120437
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