Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma

BACKGROUND: Boron neutron capture therapy (BNCT) is a unique particle radiation therapy based on the nuclear capture reactions in boron-10. We developed a novel boron-10 containing sodium borocaptate (BSH) derivative, 1-amino-3-fluorocyclobutane-1-carboxylic acid (ACBC)-BSH. ACBC is a tumor selectiv...

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Detalhes bibliográficos
Publicado no:Radiat Oncol
Main Authors: Futamura, Gen, Kawabata, Shinji, Nonoguchi, Naosuke, Hiramatsu, Ryo, Toho, Taichiro, Tanaka, Hiroki, Masunaga, Shin-Ichiro, Hattori, Yoshihide, Kirihata, Mitsunori, Ono, Koji, Kuroiwa, Toshihiko, Miyatake, Shin-Ichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260095/
https://ncbi.nlm.nih.gov/pubmed/28114947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-017-0765-4
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