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Whole-Transcriptome Analysis in Peripheral Blood Mononuclear Cells from Patients with Lipid-Specific Oligoclonal IgM Band Characterization Reveals Two Circular RNAs and Two Linear RNAs as Biomarkers of Highly Active Disease

The presence of anti-myelin lipid-specific oligoclonal IgM bands (LS-OCMBs) has been defined as an accurate predictor of an aggressive evolution of multiple sclerosis. However, the detection of this biomarker is performed in cerebrospinal fluid, a quite invasive liquid biopsy. In the present study w...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Iparraguirre, Leire, Olaverri, Danel, Blasco, Telmo, Sepúlveda, Lucía, Castillo-Triviño, Tamara, Espiño, Mercedes, Costa-Frossard, Lucienne, Prada, Álvaro, Villar, Luisa María, Otaegui, David, Muñoz-Culla, Maider
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759842/
https://ncbi.nlm.nih.gov/pubmed/33255923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8120540
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