Hypoxia-Preconditioned Wharton's Jelly-Derived Mesenchymal Stem Cells Mitigate Stress-Induced Apoptosis and Ameliorate Human Islet Survival and Function in Direct Contact Coculture System

Protection of isolated pancreatic islets against hypoxic and oxidative damage-induced apoptosis is essential during a pretransplantation culture period. A beneficial approach to maintain viable and functional islets is the coculture period with mesenchymal stem cells (MSCs). Hypoxia preconditioning...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Keshtkar, Somayeh, Kaviani, Maryam, Jabbarpour, Zahra, Sabet Sarvestani, Fatemeh, Ghahremani, Mohammad Hossein, Esfandiari, Elaheh, Hossein Aghdaei, Mahdokht, Nikeghbalian, Saman, Shamsaeefar, Alireza, Geramizadeh, Bita, Azarpira, Negar
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759420/
https://ncbi.nlm.nih.gov/pubmed/33381188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8857457
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