Sevoflurane preconditioning attenuates hypoxia/reoxygenation injury of H9c2 cardiomyocytes by activation of the HIF-1/PDK-1 pathway

BACKGROUND: Sevoflurane preconditioning (SPC) can provide myocardial protective effects similar to ischemic preconditioning (IPC). However, the underlying molecular mechanism of SPC remains unclear. Studies confirm that hypoxia-inducible factor-1 (HIF-1) can transform cells from aerobic oxidation to...

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Udgivet i:PeerJ
Main Authors: Hou, Tianliang, Ma, Haiping, Wang, Haixia, Chen, Chunling, Ye, Jianrong, Ahmed, Ahmed Mohamed, Zheng, Hong
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2020
Fag:
Biochemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759118/
https://ncbi.nlm.nih.gov/pubmed/33391885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10603
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