Lyophilized Amorphous Dispersion of Telmisartan in a Combined Carrier–Alkalizer System: Formulation Development and In Vivo Study

[Image: see text] Telmisartan suffers from low oral bioavailability due to its poor water solubility. The research work presents a formulation of solid dispersed (SD) telmisartan formulation as a ternary mixture of a drug, a polymeric carrier (poly(vinylpyrrolidone) (PVP) K30), and an alkalizer (Na(...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Al-Japairai, Khater A. S., Alkhalidi, Hala M., Mahmood, Syed, Almurisi, Samah H., Doolaanea, Abd Almonem, Al-Sindi, Taha A., Chatterjee, Bappaditya
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758947/
https://ncbi.nlm.nih.gov/pubmed/33376884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04588
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