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Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer

Tamoxifen is a drug commonly used in the treatment of breast cancer, especially for postmenopausal patients. However, its efficacy is limited by the development of drug resistance. Downregulation of estrogen receptor alpha (ERα) is an important mechanism of tamoxifen resistance. In recent years, wit...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Yao, Jingwei, Deng, Kun, Huang, Jialu, Zeng, Ruimin, Zuo, Jianhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758911/
https://ncbi.nlm.nih.gov/pubmed/33362547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.592912
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