Preclinical and first-in-human-brain-cancer applications of [(18)F]poly (ADP-ribose) polymerase inhibitor PET/MR

BACKGROUND: We report preclinical and first-in-human-brain-cancer data using a targeted poly (ADP-ribose) polymerase 1 (PARP1) binding PET tracer, [(18)F]PARPi, as a diagnostic tool to differentiate between brain cancers and treatment-related changes. METHODS: We applied a glioma model in p53-defici...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Young, Robert J, Demétrio De Souza França, Paula, Pirovano, Giacomo, Piotrowski, Anna F, Nicklin, Philip J, Riedl, Christopher C, Schwartz, Jazmin, Bale, Tejus A, Donabedian, Patrick L, Kossatz, Susanne, Burnazi, Eva M, Roberts, Sheryl, Lyashchenko, Serge K, Miller, Alexandra M, Moss, Nelson S, Fiasconaro, Megan, Zhang, Zhigang, Mauguen, Audrey, Reiner, Thomas, Dunphy, Mark P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758909/
https://ncbi.nlm.nih.gov/pubmed/33392502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa119
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados