CNS macrophages differentially rely on an intronic Csf1r enhancer for their development

The central nervous system hosts parenchymal macrophages, known as microglia, and non-parenchymal macrophages, collectively termed border-associated macrophages (BAMs). Microglia, but not BAMs, were reported to be absent in mice lacking a conserved Csf1r enhancer: the fms-intronic regulatory element...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Munro, David A. D., Bradford, Barry M., Mariani, Samanta A., Hampton, David W., Vink, Chris S., Chandran, Siddharthan, Hume, David A., Pridans, Clare, Priller, Josef
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2020
Fag:
Research Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758622/
https://ncbi.nlm.nih.gov/pubmed/33323375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.194449
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