The Function of the Conserved Regulatory Element within the Second Intron of the Mammalian Csf1r Locus

The gene encoding the receptor for macrophage colony-stimulating factor (CSF-1R) is expressed exclusively in cells of the myeloid lineages as well as trophoblasts. A conserved element in the second intron, Fms-Intronic Regulatory Element (FIRE), is essential for macrophage-specific transcription of...

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Autores principales: Sauter, Kristin A., Bouhlel, M. Amine, O’Neal, Julie, Sester, David P., Tagoh, Hiromi, Ingram, Richard M., Pridans, Clare, Bonifer, Constanze, Hume, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561417/
https://ncbi.nlm.nih.gov/pubmed/23383005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054935
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