α-Actinin-4 Promotes the Progression of Prostate Cancer Through the Akt/GSK-3β/β-Catenin Signaling Pathway

The first-line treatment for prostate cancer (PCa) is androgen ablation therapy. However, prostate tumors generally recur and progress to androgen-independent PCa (AIPC) within 2–3 years. α-Actinin-4 (ACTN4) is an actin-binding protein that belongs to the spectrin gene superfamily and acts as an onc...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Autores principales: Park, Sungyeon, Kang, Minsoo, Kim, Suhyun, An, Hyoung-Tae, Gettemans, Jan, Ko, Jesang
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758325/
https://ncbi.nlm.nih.gov/pubmed/33363146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.588544
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